Human Papilloma Virus, Risk Factors and Sequelae: How much do Female Adolescents in Port Harcourt Metropolis know?

Authors

DOI:

https://doi.org/10.60787/tnhj.v23i1.301

Keywords:

Human Papillomavirus, cervical cancer, adolescents, Port Harcourt

Abstract

Background: Human Papilloma virus (HPV) infection is the most common viral infection of the genital tract; is sexually transmitted with the highest rates observed in young women. This study assessed the level of knowledge of HPV and cervical cancer among adolescent girls in Port Harcourt metropolis, Nigeria.

Methodology: A cross-sectional survey among 328 in-school female secondary school students aged 9 - 19 years, selected via multi-stage sampling. Information on socio-demographics, knowledge of HPV and cervical cancer and sexual history were collected using a self-administered, semi-structured questionnaire. Data was analyzed using SPSS version 23 and Chi square test was used to establish associations.

Results: Only 38.2% and 30% had heard of cervical cancer and HPV respectively; the media being the most common source. Knowledge oftransmission, risk factors, sequelae and prevention of infection was poor (75%). About 20.2% were aware of the causal association between HPV infection and cervical cancer. Some (3.1%) were sexually exposed and practiced unprotected sexual intercourse. Median age at sexual debut was 11 years. Older and private school students (15-19years) had better knowledge

Conclusion: The level of knowledge of HPV, cervical cancer, their association and risk factors, among adolescent girls in Port Harcourt metropolis is poor. Some adolescents engage in sexual practices that put them at risk for HPV infection. Social media and upper primary and secondary school-based approach to HPV health promotion should be explored to provide detailed adolescent-friendly information to guide in prevention of HPV infection and cervical cancer

Downloads

Download data is not yet available.

Author Biographies

IL Oboro, Department of Medical Microbiology and Parasitology, Rivers State University / Teaching Hospital

Associate Dean

Faculty of Basic Clinical Sciences,

College of Medical Sciences, 

Rivers State University

MA Alex-Wele, Department of Medical Microbiology, University of Port Harcourt Teaching Hospital

Head, Department of Medical Microbiology and Parasitology,

University of Port Harcourt/ Teaching Hospital

DS Ogaji, ACEPUTOR, University of Port Harcourt

Director,

Africa centre of excellence for public health and toxicological research

University of Port Harcourt

References

Nejo YT, Olaleye DO, Odaibo GN. Prevalence and Risk Factors for Genital Human PapillomavirusInfections Among Women in Southwest Nigeria. Archives of basic and applied medicine. 2018 Feb;6(1):105-12.

Toh ZQ, Kosasih J, Russell FM, Garland SM, Mulholland EK, Licciardi PV. Recombinant human papillomavirus nonavalent vaccine in the prevention of cancers caused by human papillomavirus. Infection and drug resistance. 2019; 12:1951.

Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: a cancer journal for clinicians. 2018 Nov;68(6):394-42

.4Kennedy NT, Ikechukwu D, Goddy B. Risk factors and distribution of oncogenic strains of human papilloma virus in women presenting for cervical cancer screening inPort Harcourt, Nigeria. Pan African Medical Journal. 2016 Jul 4;23(1).

Centers for Disease Control and Prevention. STD Curriculum for Clinical Educators. Genital Human papillomavirus. 2013:1-37.

Vinodhini K, Shanmughapriya S, Das BC, Natarajaseenivasan K. Prevalence and risk factors of HPV infection among women from various provinces of the world. Archives of gynecology and obstetrics. 2012 Mar;285(3):771-7.

Cervantes JL, Doan AH. Discrepancies in the evaluation of the safety of the human papillomavirus The level of knowledge of Human Papilloma virus, vaccine. Memórias do Instituto Oswaldo Cruz. 2018 May 28;113

Doufekas K, Achampong Y, Olaitan A. Prevention of Cervical Cancer. InUterine Cervical Cancer 2019 (pp. 17-29). Springer, Cham.

World Health Organization, 2021. Human Papilloma virus vaccines (HPV).Available at https://www.who.int/teams/immunization-vaccines-and-biologicals/diseases/human-Papilloma virus-vaccines-(HPV). Accessed October 7th, 2021

Grm HS, Bergant M, Banks L. Human papillomavirus infection, cancer & therapy. Indian Journal of Medical Research. 2009 Sep 1;130(3):277.

Bonnez, W. Human Papilloma virus. InVaccines for Biodefense and Emerging and Neglected Diseases; Alan, D.T., Barrett, L.R.S., Eds.; Academic Press: Cambridge, MA, USA, 2009; pp. 469–496.

ICO/IARC Information Centre on HPV and Cancer, 2019. Nigeria: Human Papilloma virus and Related Cancers, Fact Sheet 2019. Available at https://www.hpvcentre.net/statistics/reports/NGA_FS.pdf. Accessed 4th November 2020

Mahomed K, Evans D, Sauls C, Richter K, Smith J, Firnhaber C. Human papillomavirus (HPV) testing on self-collected specimens: perceptions among HIV positive women attending rural and urban clinics in South Africa. The Pan African medical journal. 2014;17.

Schmitt M, Depuydt C, Benoy I, Bogers J, Antoine J, Arbyn M, Pawlita M, VALGENT Study Group.

Prevalence and viral load of 51 genital human papillomavirus types and three subtypes. International journal of cancer. 2013 May 15;132(10):2395-403.

Bosch FX, Lorincz A, Muñoz N, Meijer CJ, Shah KV. The causal relation between human papillomavirus and cervical cancer. Journal of clinical pathology. 2002 Apr 1;55(4):244-65.

Bardají A, Mindu C, Augusto OJ, Casellas A, Cambaco O, Simbine E, Matsinhe G, Macete E, Menéndez C, Sevene E, Munguambe K. Awareness of cervical cancer and willingness to be vaccinated against human papillomavirus in Mozambican adolescent girls. Papillomavirus Research. 2018 Jun 1;5:156-62.

World Health Organization, 2019. Human Papilloma virus (HPV) and Cervical cancer. Available at https://www.who.int/news-room/fact-sheets/detail/human-Papilloma virus-(hpv)-and-cervical-cancer. Accessed October 25th, 2021.

ICO/IARC Information Centre on HPV and Cancer, 2021. Nigeria: Human Papilloma virus and Related Cancers, Fact Sheet 2021. Available at https://hpvcentre.net/statistics/reports/NGA_FS.pdf. Accessed 15th October, 2021.

Schiffman M, Wentzensen N. Human papillomavirus infection and the multistage carcinogenesis of cervical cancer. Cancer epidemiology, biomarkers & prevention. 2013 Apr;22(4):553-60.

Kjaer SK, Chackerian B, Van Den Brule AJ, Svare EI, Paull G, Walbomers JM, Schiller JT, Bock JE, Sherman ME, Lowy DR, Meijer CL. High-risk human papillomavirus is sexually transmitted: Evidence from a follow-up study of virgins starting sexual activity (Intercourse). Cancer Epidemiology Biomarkers and Prevention. 2001;10(2):101-6.

Alex-Hart BA, Okagua J, Opara PI. Sexual behaviours of secondary school students in Port Harcourt.Journal of Advances in Medicine and Medical Research. 2015;325-334.

Okonta PI. Adolescent sexual and reproductive health in the Niger Delta region of Nigeria-Issues and challenges. African journal of reproductive health. 2007 Apr 1;11(1):113-24.

Ojule IN, Anika IE. Human Papilloma Virus Transmission: Knowledge and Uptake of HPV Vaccine Among In-School Adolescent Girls in South-South Nigeria. International Journal of tropical disease & Health. 2020;41(8): 25-37

Saha A, Chaudhury AN, Bhowmik P, Chatterjee R. Awareness of cervical cancer among female students of premier colleges in Kolkata, India. Asian Pac J Cancer Prev. 2010 Jan 1;11(4):1085-90.

Turiho AK, Muhwezi WW, OkelloES, Tumwesigye NM, Banura C, Katahoire AR. Human papillomavirus (HPV) vaccination and adolescent girls' knowledge and sexuality in Western Uganda: A comparative cross-sectional study. PloS one. 2015 Sep 1;10(9):e0137094.

Sadoh AE, Okonkwo C, Nwaneri DU,Ogboghodo MB, Eregie C, Oviawe O, Famuyiwa MO. Effect of peer education on knowledge of human papilloma virus and cervical cancer among female adolescent students in Benin City, Nigeria. Annals of global health. 2018;84(1):121.

Ifediora CO, Azuike EC. Knowledge and attitudes about cervical cancer and its prevention among female secondary school students in Nigeria. Tropical Medicine & International Health. 2018 Jul;23(7):714-23.

Oboro IL, Athanasius BP. Awareness of Cervical Cancer Screening and Prevention among Students of a Tertiary Institution in Southern Nigeria. Journal of cancer and tumor international. 2020;10 (1), 26-32

Mburu A, Itsura P, Mabeya H, Kaaria A, Brown DR. Knowledge of cervical cancer and acceptability of prevention strategies among human Papillomavirus-Vaccinated and human Papillomavirus-Unvaccinated adolescent women in Eldoret, Kenya. BioResearch open access. 2019 Aug 20;8(1):139-45.

Ahlawat P, Batra N, Sharma P, Kumar S, Kumar A. Knowledge and attitude of adolescent girlsand their mothers regarding Cervical Cancer: a community-based cross-sectional study. Journal of Mid-life Health. 2018 Jul;9(3):145.

Lee A, Ho M, Cheung CKM, Keung VMW. Factors influencing adolescent girls’ decision in initiation for human Papilloma virus vaccination: a cross-sectional study in Hong Kong.BMC public health.2014;14(1):1-10.

Navarro-Illana P, Diez-Domingo J, Navarro-Illana E, Tuells J, Alemán S, Puig-Barberá J. Knowledge and attitudes of Spanish adolescent girls towards human papillomavirus infection: where to intervene to improve vaccination coverage. BMC public health. 2014 Dec;14(1):1-8.

Ozyer S, Uzunlar O, Ozler S, Kaymak O, Baser E, Gungor T, Mollamahmutoglu L. Awareness of Turkish female adolescents and young women about HPV and their attitudes towards HPV vaccination. Asian Pacific Journal of cancer prevention. 2013;14(8):4877-81.

Bodajko-Grochowska A, Bednarek A, Markut-Miotła E, Zarzycka D. Knowledge of cervical cancer prevention among teenagers.Cancer Treatment and Research.2017;3(1):22-30.

Gualano MR, Stillo M, Mussa MV, Zotti CM. Cross sectional study investigating the differences in knowledge and behaviors about HPV between vaccinated and non-vaccinated girls. Journal of preventive medicine and hygiene. 2016 Sep;57(3):E121

Abdi F, Simbar M. The peer education approach in adolescents-narrative review article. Iranian journal of public health. 2013 Nov;42(11):1200.

Adeomi AA, Adeoye OA, Asekun-Olarinmoye EO, Abodunrin OL, Olugbenga-Bello AI, Sabageh AO. Evaluation of the effectiveness of peer education in improving HIV knowledge, attitude, and sexual behaviours among in-school adolescents in Osun State, Nigeria. AIDS research and treatment. 2014 Nov 13;2014.

Sánchez-Alemán MA, Uribe-Salas FJ, Lazcano-Ponce EC, García-Cisneros S, Eguiza-Fano S, Conde-Glez CJ. HSV-2 seroincidence among Mexican college students: the delay of sexual debut is not enough to avoid risky sexual behaviours and virus transmission. Sexually transmitted infections. 2010 Dec 1;86(7):565-9.

Downloads

Published

2023-03-11 — Updated on 2023-03-16

Versions

How to Cite

Oboro, I. L., Alex-Wele, M. A., & Ogaji, D. samuel. (2023). Human Papilloma Virus, Risk Factors and Sequelae: How much do Female Adolescents in Port Harcourt Metropolis know?. The Nigerian Health Journal, 23(1), 452–459. https://doi.org/10.60787/tnhj.v23i1.301 (Original work published March 11, 2023)

Issue

Section

Original Articles
Abtract Views | PDF Download | EPUB Download: 683 / 160

Similar Articles

1 2 3 4 5 6 7 8 9 10 > >> 

You may also start an advanced similarity search for this article.