Sero-epidemiology ofToxoplasmosis among Pregnant women receiving antenatal care in the University of Port Harcourt Teaching Hospital

Authors

  • Ibinabo Laura Oboro University of Port Harcourt Teaching Hospital/ University of Port Harcourt, Alakahia, Rivers State, Nigeria.
  • Orikomaba Korifama Obunge University of Port Harcourt Teaching Hospital/ University of Port Harcourt, Alakahia, Rivers State, Nigeria
  • Kennedy Tamunoimiegbam Wariso University of Port Harcourt Teaching Hospital/ University of Port Harcourt, Alakahia, Rivers State, Nigeria

DOI:

https://doi.org/10.60787/tnhj.v16i1.203

Keywords:

Toxoplasma gondii, Pregnancy, ELISA, Risk factors

Abstract

Objectives: To determine the sero-prevalence of Toxoplasma gondii infection and associated risk factors among pregnant women in the University of Port Harcourt Teaching Hospital, Nigeria.


Methods: This cross-sectional study carried out in 2013 involved two hundred and eighty-eight (288) pregnant women who gave informed consent. Questionnaires were administered to determine their socio-demographic and risk factors. Enzyme-linked immunosorbent assay (ELISA) was performed on all patients’ sera to detect anti-Toxoplasma Immunoglobulin G (IgG) and M (IgM). Data was analyzed using the statistical package Epi info version 6.04d.


Results: A total of one hundred and eighty-nine women (65.6 %) were sero-positive for IgM and/or IgG. Thirty-three (11.5%) were positive for IgM only, one hundred and twenty-three (42.4%) for IgG only and thirty-three (11.5%) for both. Consumption of beef was a statistically significant risk factor associated.


Conclusion: A significant proportion of pregnant women have been exposed to Toxoplasma gondii, with the risk factor significantly associated with infection being consumption of beef, this being very common practice in Port Harcourt. It is therefore necessary to heighten enlightenment of the populace particularly women of child-bearing age and pregnant women on toxoplasmosis –specific preventive practices to reduce their exposure to the pathogen and its potential complications. Women with poor obstetric history may benefit from screening for Toxoplasma gondii as part of their management.

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Author Biographies

Ibinabo Laura Oboro, University of Port Harcourt Teaching Hospital/ University of Port Harcourt, Alakahia, Rivers State, Nigeria.

Consultant Clinical Microbiologist and Lecturer I,

Department of Medical Microbiology and Parasitology,

University of Port Harcourt Teaching Hospital/ University of Port Harcourt

Orikomaba Korifama Obunge, University of Port Harcourt Teaching Hospital/ University of Port Harcourt, Alakahia, Rivers State, Nigeria

Consultant Clinical Microbiologist and Professor,

Department of Medical Microbiology and Parasitology,

University of Port Harcourt Teaching Hospital/ University of Port Harcourt

Kennedy Tamunoimiegbam Wariso, University of Port Harcourt Teaching Hospital/ University of Port Harcourt, Alakahia, Rivers State, Nigeria

Consultant Clinical Microbiologist and Senior Lecturer,

Department of Medical Microbiology and Parasitology,

University of Port Harcourt Teaching Hospital/ University of Port Harcourt

References

Hokelek, Murat, Amar Safdar. “Toxoplasmosis” (internet). eMedicine; 2004, Aug 10. (Assessed February 16th, 2011). Available at http://emedicine.com/ped/topic271/htm.

Centres for disease control and prevention. Toxoplasmosis. 2010, 2 Nov. (Assessed Feb 18 2011). Available from http://www.cdc.gov/parasites/toxoplasmosis/epi.html.

Feldman HA. Toxoplasmosis: an overview. Bull N Y Acad Med.1974; 50:110-127.

Perry DD and Meritt JC. Congenital ocular toxoplasmosis. J Natl Med Assoc. 1983; 75(2):169-174.

Kravetz JD and Federman DG. Toxoplasmosis in pregnancy. The Am J Med. 2005; 118:212–216.

Ayi I, Edu SAA, Apea-kubi KA, Boamah D, Bosompem KM, Edoh D. Toxoplasmosis in pregnant women in Ghana. Gh Med J. 2009; 43(3):107-114.

Spalding SM, Amendoeira MRR, Klein CH, Ribeiro LC. Serological screening and toxoplasmosis exposure factors among pregnant women in South of Brazil. Rev Soc Bras Med Trop. 2005;38(2):173-177.

Akinbami AA, Adewunmi AA, Rabiu KA, Wright KO, Dosunmu AO, Dada MO, Adeyemo TA. Seroprevalence of Toxoplasma gondii Antibodies amongst Pregnant Women at the Lagos State University Teaching Hospital, Nigeria. Niger Postgrad Med J. Jun 2010; 17(2):160-3.

Ishaku BS, Ajogi I, Umoh JU, Lawal I, Randawa AJ. Seroprevalence and Risk Factors for Toxoplasma gondii Infection among Antenatal Women in Zaria, Nigeria. Res J Med Med Sci. 2009; 4(2):483-488.

Onadeko MO, Joynson DH, Payne RA, Francis J. The prevalence of Toxoplasma antibodies in pregnant Nigerian women and the occurrence of stillbirth and congenital malformation. Afr J Med Med Sci. Dec 1996; 25(4):331-4.

Olusi T, Gross U, Ajayi J: High incidence of toxoplasmosis during pregnancy in Nigeria. Scand J Infect Dis. 1996;28:645

Arene FOI . The prevalence and public health significance of Toxoplasma gondii in domestic cats in the Niger Delta. Public Health. Nov 1984; 98(6):333-335.

Adesiyun AA, Gooding R, Ganta K, Seepersadsingh N, Ramsewak S. Congenital toxoplasmosis in two health institutions in Trinidad. West Ind Med J. 2007; 56(2):166-170.

Marcinek P, Nowakowska D, Szaflik K, Spiewak E, Małafiej E, Wilczyński J. Analysis of complications during pregnancy in women with serological features of acute toxoplasmosis or acute parvovirosis. Ginekol Pol. 2008 Mar; 79(3):186-91.

Mitchell CD, Erlich SS, Mastrucci MT, Hutto SC, Parks WP, Scott GB. Congenital toxoplasmosis occurring in infants perinatally infected with human immunodeficiency virus 1. Pediatr Infect Dis J. 1990; 9:512-8.

Falusi O, French AL, Seaberg EC, Tien PC, Watts DH, Minkoff H, Piessens E, Kovacs A, Anastos K, Cohen MH. Prevalence and Predictors of Toxoplasma Seropositivity in Women with and at Risk for Human Immunodeficiency Virus Infection. Clin Infect Dis. 2002; 35(11):1414-1417.

Akani CI, Ojule AC, Opurum HC, John CT. Sero-prevalence of HIV antibodies in pregnant women in Port Harcourt, Nigeria. Niger J Med. 2006; 15(1):44-8.

Pappas G, Roussos N, Matthew E, Falagas ME. Toxoplasmosis snapshots: Global status of Toxoplasma gondii seroprevalence and implications for pregnancy and congenital toxoplasmosis. © 2009 Australian Society for Parasitology Inc., Elsevier Ltd. Int J parasitol. 2009; 39(12):1385-1394.

da Silva LB, de Oliveira Rde V, da Silva MP, Bueno WF, Amendoeira MR, de Souza Neves E. Knowledge of toxoplasmosis among doctors and nurses who provide prenatal care in an endemic region. Infect Dis Obstet Gynecol. 2011; 2011:750484.

Pereboom MT, Manniën J, Spelten ER, Schellevis FG, Hutton EK. Observational study to assess pregnant women's knowledge and behaviour to prevent toxoplasmosis, listeriosis and cytomegalovirus. BMC Pregnancy Childbirth. 2013 Apr 30; 13:98.

Pawlowski ZS, Gromadecka-Sutkiewicz M, Skommer J, Paul M, Rokossowski H, Suchocka E, Schantz PM. Impact of health education on knowledge and prevention behaviour for congenital toxoplasmosis: the experience of Poznan Poland. Health Educ Res. 2001 Aug;16(4):493-502

Foulon W, Naessens A, Ho-Yen D. Prevention of congenital toxoplasmosis. J Perinat Med.2000; 28:337-345.

Baril L, Ancelle T, Goulet V. Risk factors for Toxoplasma infection in pregnancy: a case-control study in France. Scand J Infect Dis. 1999; 31:305–309.

Cook AJ, Gilbert RE, Buffolano W, Zufferey J, Petersen E, Jenum PA, Foulon W, Semprini AE, Dunn DT. Sources of toxoplasma infection in pregnant women: European multicentre case-control study. BMJ 2000 Jul 15; 321(7254): 142-147.

Foulon W, Naessens A, Lauwers S, De Meuter F, Amy JJ. Impact of primary prevention on the incidence of toxoplasmosis during pregnancy. Obstet Gynecol.1988; 72(3 pt 1)363-366.

McCabe and Remington J.S. Toxoplasmosis: the time has come. N Engl J Med. 1988; 318(5)313-315.

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Published

2016-10-24

How to Cite

Oboro, I. L., Obunge, O. K., & Wariso, K. T. (2016). Sero-epidemiology ofToxoplasmosis among Pregnant women receiving antenatal care in the University of Port Harcourt Teaching Hospital. The Nigerian Health Journal, 16(1), 32. https://doi.org/10.60787/tnhj.v16i1.203
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