Patterns of Arrythmias among HIV infected Patients on Highly Active Antiretroviral Therapy (HAART) and its Relationship with CD4 Cells Count and Viral load in a Tertiary Hospital in North Eastern Nigeria

Pattern of arrhythmias among HIV infected patients on HAART

Authors

  • Baba MM Department of Medicine, Yobe State University College of Medical Sciences, Damaturu, Nigeria
  • Abdul H Department of Medicine, Yobe State University College of Medical Sciences, Damaturu, Nigeria
  • Ayoola YA Department of Medicine, Gombe State University College of Medical Sciences Gombe, Nigeria
  • Goni BW Department of Medicine, Yobe State University College of Medical Sciences, Damaturu, Nigeria
  • Mairari FG Department of Physiology, Yobe State University College of Medical Sciences, Nigeria

DOI:

https://doi.org/10.60787/tnhj.v24i3.836

Keywords:

Arrhythmia, HIV, Highly Active Antiretroviral Therapy, CD4 cells count, viral load

Abstract

Background: Human immunodeficiency virus (HIV) pandemic continues to be a major public health problem globally. The advent of highly active antiretroviral therapy has changed the natural history of HIV as well as the morbidity and mortality associated with the disease. However, patients living with HIV infection remain at increased risk of cardiovascular diseases and sudden cardiac death. Diverse electrocardiographic abnormalities were reported among HIV infected patients. However, to the best of our knowledge, there are few studies on patterns of arrhythmias among HIV infected patients in northeastern part of Nigeria.

Method: It was a cross-sectional study conducted among HIV infected patients receiving highly active anti-retroviral therapy (HAART) at the Federal Medical Centre Nguru, Yobe State, North Eastern Nigeria.

Result: One hundred (100) subjects were recruited into the study comprising thirty-three (33.0%) males and 67(67.0%) females. The mean CD4 cells count and viral load of the studied patients were 614.99 ± 34.92 cells/μL and 4654±58.79 copies/mL, respectively. The commonest cardiac rhythm was sinus rhythm, followed by sinus tachycardia and atrial fibrillation. Other abnormalities observed includes: First degree atrioventricular block, nonspecific intraventricular conduction defect, right bundle branch block, left bundle branch block and left posterior hemi block.

Conclusion: In conclusion, the study revealed that premature ventricular contractions both (unifocal and multifocal) are the commonest cardiac arrhythmias, while sinus tachycardia and non-specific intraventricular conduction defect are the second common cardiac arrhythmias, the study further revealed that low CD4 cells count and high viral load were found to be associated with diverse cardiac arrhythmias.

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Author Biographies

Abdul H, Department of Medicine, Yobe State University College of Medical Sciences, Damaturu, Nigeria

Consultant Cardiologist

Ayoola YA, Department of Medicine, Gombe State University College of Medical Sciences Gombe, Nigeria

Senior Lecturer

Goni BW, Department of Medicine, Yobe State University College of Medical Sciences, Damaturu, Nigeria

Associate Professor, Chief Medical Director, Consultant

Mairari FG, Department of Physiology, Yobe State University College of Medical Sciences, Nigeria

Lecturer II

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Published

2024-10-09

How to Cite

Baba, M. M., Abdul, H., Ayodele, A. Y., Goni, B. W., & Mairari, F. G. (2024). Patterns of Arrythmias among HIV infected Patients on Highly Active Antiretroviral Therapy (HAART) and its Relationship with CD4 Cells Count and Viral load in a Tertiary Hospital in North Eastern Nigeria: Pattern of arrhythmias among HIV infected patients on HAART. The Nigerian Health Journal, 24(3), 1423–1430. https://doi.org/10.60787/tnhj.v24i3.836

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