The Prevalence of Malaria Antigen in The Serum of HIV Seropositive Patients In Port Harcourt


  • Kennedy Tamunomiebam Wariso Departments of Medical microbiology and Parasitology, University of Port Harcourt Teaching Hospital, Port Harcourt
  • Chijoke Adonye Nwauche Department of Hematology and Blood Transfusion, University of Port Harcourt Teaching Hospital, Port Harcourt


HIV, Seropositive, Prevalence


Background: Malaria and HIV infections are now endemic in Sub-Saharan Africa. The morbidity and mortality of each infection is high in tropical Africa. Therefore, a co-infection of both will be expected to present a gloomy picture. The aim of this study was to determine the prevalence of adult HIV seropositive patients with malaria antigen.

Methodology: 300 adults who were HIV seropositive were randomly selected and screened for malaria antigen, using the rapid diagnostic test technique on blood obtained through a finger prick, in the clinic.

Results: A total of 79 patients were positive, with a prevalence of 26.5%.

Conclusion: The prevalence of 26.5% obtained is similar to that obtained in Jos, Nigeria (21%).There seems to be no difference in the prevalence rate of HIV infected patients with malaria and those that are seronegative for HIV.


Global Strategic Plan (2005-2015) for the roll back malaria partnership. WHO 2005:4-44.

Global guidelines to monitor progress on the implementation of the 2011political declaration on HIV/AIDS. UNAIDS June 2011:3-55.

Global surveillance of HIV/AIDS and STI working group. AIDS epidemic update. 2010 report:5-99.

Malaria and HIV/AIDS interactions and their implications for Public Health Policy. WHO 2005:1-55.

Lester RT, Morris CN and Chakaniza H. Over diagnosis ndof presumptive malaria on a sugar estate in Malawi. 42Interscience conference on Antimicrobial Agents and Chemotherapy, 2002. San Diego.

Cook GC, Nicholas JW and Zunk A. Malaria. Manson's nd text book of tropical diseases, 22edition, London, Saunders:1201-1210.

Wariso KT. Comparison between malaria parasite positivity by light microscopy and rapid antigen test among suspected malaria patients in University of Port Harcourt Teaching Hospital: TNHJ 2007;7 (3&4) :491-494.

Federal Ministry of Health, Nigeria. National Malaria and Vector Control Division. Report on malaria control strategies in Nigeria, 2005.

Atzori C; Bruno A, Chichino G, Cevini C, Bernuzzi AM, Gatti S, Cornolli G, and Scaglia M. HIV 1 and parasitic infections in rural Tanzania. Ann Trop Med Parasitol 1993; 87(6): 585-593.

Niyongabo T, Deloron P, Aubry P, Ndarugirire F, Manirakiza F, Muhirwa G, Ndayiragije A and Brelivet JC . Prognostic indicators in adult cerebral malaria, a study in Burundi; an area of high prevalence of HIV infection. Acta Trop 1994; 56(4): 299-305.

Francesconi P, Fabiani M, Dente MG, Lukwiya M, Okwey R, Ouma J, Ochakachon R, Cian F and Declich S. HIV, malaria parasites and acute febrile episodes in Ugandan adults: a case control study. AIDS 2001; 15(18): 2445-2450.

French N, Nakiyingi J, Lugada E, Watera C, Whitworth J and Gilks C. Increasing rates of malarial fever with deteriorating immune status in HIV 1 infected Ugandan adults. AIDS 2001;15(7): 899-906.

Muller O, Moser R. The clinical and parasitological presentation of Plasmodium falciparum malaria in Uganda is unaffected by HIV 1 infection. The Transactions of the Royal Society of Tropical Medicine and Hygiene. 1990; 84 (3):336-338.

Francine HV, Bernard JB, Hart CA, Lyson C, Kazembe P, Broadhead RL. Increased prevalence of malaria in HIV infected pregnant women and its implications for malaria control. European Journal of Tropical Medicine and International Health 1999; 4(1): 5-12.

Igbeneghu C, Odiabo AB, Olaleye DO, Onuegbu J and Olisekadiaha J. Relationship between fever, malaria and HIV infection in a semi urban community in South Western Nigeria. World Journal of Medical Sciences; 2010, 5 (2): 41-44.

Kapito- Tembo A, Meshnick SR, Van Hensbroek MB, Phiri K, Fitzgerald M. Malaria and anaemia in HIV infected pregnant women taking cotrimoxazole with or without sulfadoxine-pyrimethamine intermittent preventive therapy during pregnancy in Malawi. Journal of infectious Disease 2011; 203 (4): 464-472.

Muema DK, Ndungu FM, Kinyanjui SM and Berkley JA. Effect of HIV infection on the acute antibody response to malaria antigens in children: an observational study. Malaria Journal 2011; 5:10-55.

World Health Organization. WHO expert committee on thmalaria; 20 report, WHO Technical Report series, 2000: 892.

Moody A. A Rapid diagnostic test for malaria parasite. Clinical Microbiology Review 2002: 66-78.

Makler MT,Howard RI, Moody A, et al. A Review ofPractical Techniques for the diagnosis of malaria. Annals of tropical medicine and Parasitology 1998; 92: 419-433.

Van Geertruyden JP, Moody A, Muema DK, et al. The relationship of Plasmodium falciparum humoral immunity with HIV 1 immunosuppression and treatment efficacy in Zambia. Malaria Journal 2009;20( 8):258.

Howard RJ, Makler MT, Deressa W, et al. Secretion ofmalaria Histidine Rich Protein 11 (Pf HRP 11) from Plasmodium infected erythrocyte. Journal of cell Biology 1986;103: 1269-1277.

Addissie A, Sellessie FE, Deressa W. Malaria and HIV co-infection in Hadya zone, Southern Ethiopia. Ethiop Med J 2007; 45 (1): 9-17.

Uneke CJ, Ogbua O, Inyama PU , Anyanwu GI. Malaria infection in HIV-seropositive and HIV seronegative individuals in Jos, Nigeria. J Vect Borne Dis 2005; 42:151-154.

Grobusch MP, Makler MT, Deressa W, et al. False positive Rapid test for malaria in patients with rheumatoid factor. Lancet 1999:353-397




How to Cite

Wariso, K. T., & Nwauche, C. A. (2015). The Prevalence of Malaria Antigen in The Serum of HIV Seropositive Patients In Port Harcourt. The Nigerian Health Journal, 11(4), 120. Retrieved from

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