Antibacterial Activity of Ethanolic and Aqueous Extracts of Zingiber officinale Roscoe on Selected Bacterial Isolates
DOI:
https://doi.org/10.71637/tnhj.v25i2.1076Keywords:
Bacteria, Zingiber officinale Roscoe, Ethanolic extract, Aqueous extract, Zone of Inhibition, CiprofloxacinAbstract
Background: Zingiber officinale Roscoe (Ginger) is a spice commonly known for its nutritional and flavouring value. This study was carried out to assess the antibacterial activities of the ethanolic and aqueous extracts of Zingiber officinale Roscoe on selected bacteria isolates.
Materials and Methods: Swab samples were taken to the laboratory for culturing and isolation. The zones of inhibition of the ethanolic and aqueous extracts of Zingiber officinale Roscoe on four selected bacteria isolates from the swab samples were tested for antibacterial activity.
Results: The ethanolic extract of Zingiber officinale Roscoe exhibited antibacterial activity against all the bacterial isolates at concentrations of 100, 50, and 25 mg/ml. There was no antibacterial activity at 12.5 mg/ml and 6.25 mg/ml. The aqueous extract of Zingiber officinale Roscoe exhibited antibacterial activity against all the bacterial isolates at concentrations of 100 mg/ml and 50 mg/ml. There was no antibacterial activity at concentrations of 25, 12.5, and 6.25 mg/ml. Ciprofloxacin, which served as a control, exhibited antibacterial activity at all concentrations on the selected bacterial isolates. The antibacterial activity of ciprofloxacin was significantly higher (P ˂ 0.05) than the ethanolic and aqueous extracts of Zingiber officinale Roscoe.
Conclusion: The ethanolic and aqueous extracts of Zingiber officinale Roscoe showed antibacterial activity at 100 mg/ml and 50 mg/ml concentrations on the selected bacteria isolates. These findings support the potential of Zingiber officinale Roscoe as alternative therapeutic agent against bacterial infections.
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